Researchers developed a light-driven chemical reaction that expands the range of compounds compatible with DNA-encoded libraries. The…
Researchers developed a light-driven chemical reaction that expands the range of compounds compatible with DNA-encoded libraries. The method couples carbonyl compounds under mild, room-temperature conditions while largely preserving DNA integrity, enabling broader chemical diversity for large-scale drug discovery screens. https://pubs.acs.org/jacsat/article/148/34/37235/5328162/Reductive-Couplings-Via-Nucleophilic
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