POPA ReconResearchers identified a previously unrecognized pathway that may contribute to immune dysfunction in people with Down syndrome. Analysis…
Researchers identified a previously unrecognized pathway that may contribute to immune dysfunction in people with Down syndrome. Analysis of blood samples from 270 individuals with Down syndrome found elevated activity of the chromosome 21 gene SOD1, which may increase hydrogen sulfide production through an alternative metabolic pathway. The mechanism could help explain chronic inflammation, infection susceptibility and accelerated immune aging. https://www.nature.com/articles/s41598-026-45627-6
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