POPA ReconResearchers identified tryptamine (TrpA) as a natural molecule that builds up with wakefulness and signals the brain's increasing need for…
Researchers identified tryptamine (TrpA) as a natural molecule that builds up with wakefulness and signals the brain's increasing need for sleep. Activating its receptor, GPR139, improved sleep duration and quality in mice and pigs, highlighting a promising target for new non-addictive sleep therapies. https://www.nature.com/articles/s41593-026-02332-x
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